A Randomized, Double-blind, Placebo-Controlled Trial of Terminalia Chebula and Terminalia Bellerica For Hyperuricemia

Natural Products Offer Alternative to Allopurinol and Febuxostat for Gout

May 12, 2025

∙ Paid

Upgrade to paid to play voiceover

By Peter A. McCullough, MD, MPH

One of the great privileges of practicing medicine is the opportunity to learn from patients. I had a patient recently who told me a wonderful story of controlling gout flares by lowering uric acid in the blood naturally. I wondered if there were any randomized trial evidence.

Usharani P, Nutalapati C, Pokuri VK, Kumar CU, Taduri G. A randomized, double-blind, placebo-, and positive-controlled clinical pilot study to evaluate the efficacy and tolerability of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica in subjects with hyperuricemia. Clin Pharmacol. 2016 Jun 22;8:51-9. doi: 10.2147/CPAA.S100521. PMID: 27382337; PMCID: PMC4922806.

Keep reading with a 7-day free trial

Subscribe to FOCAL POINTS (Courageous Discourse) to keep reading this post and get 7 days of free access to the full post archives.