72 Comments
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The Green Hornet's avatar

So the conspiracy theory of genetic integration becomes reality?

Color me shocked. 🙄

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Lisa Novakowski's avatar

I would say not shocked at all.

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jgr's avatar
4hEdited

This has completely transformed my life in the last 3 weeks... ketoburnblueprint.com/6khn7

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Paul Vonharnish's avatar

"Color me shocked." Heh, heh... Good one.

"When will science get enough reality to understand that it exists?" - Paul Vonharnish - (10/8/2014)

The *reality* that man's value systems are completely bogus, insane, and detached from the presence of infinite systems, hasn't occurred to anyone in the readers comments thus far. Perhaps more scientific study would point out the obvious...

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Lisa Novakowski's avatar

Hoe can this not be criminal? Yet, there is immunity for some and a captured legal system. The hard lesson is do not trust a global organization that declares an emergency.

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Jennifer Collins Brever's avatar

It is criminal and psychopathic.

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AwakeNotWoke's avatar

Maybe it's just a coincidence but in a lot of countries where mean IQ is above 100 such as Communist China, Iran, Russia, Serbia, Belarus, Mongolia and Slovenia, mRNA vaccines were either not used or non-mRNA were also offered whereas in countries where mean IQ is subnormal, such as the United States, mRNA and AVV shots were the only shots on offer.

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LONG In The TRUTH's avatar

.....ALL, systematically sought - or CONTROLLED by the Rockefeller interlocking directorate / European imperialists / philanthropaths (particularly China) - for ANNEXATION a CENTURY-plus now, and REASONS which reach back MILLENNIA.....

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Ollie's avatar

So right you are.

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Jennifer Collins Brever's avatar

I doubt it is coincidence. Where is the information from about IQ?

White Americans are the last to wake up. We were rode-out to the last act thinking we were saviors of the 3rd worlds brown people.

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Carol Taylor's avatar

Canada, UK, Australia, New Zealand all been taken in on the Hoax!

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Lisa Novakowski's avatar

I totally agree.

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Brandon is not your bro's avatar

Great paper/ study , grateful. Continue to expose the death darts .

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Crixcyon's avatar

As I recall, there were some 1,200 listed possible reactions to fizer's mRNA poisons after they did the fake trials. Are we going to see all of them take hold?

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Ric Palmer's avatar

The people who are responsible for these vaccines should be exposed and removed from control. This is the worst form of population control. Would you watch this if it were a movie?

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Paul Vonharnish's avatar

The people responsible for vaccines are insane and should meet with permanent confinement in rubber rooms. Basket weaving and leather-work lessons could be optional.

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Allie's avatar

I don’t think 10 subjects out of a total of 813 will impress enough people. What would be more impressive would be if you demonstrated these same findings to be significantly greater in “vaccinated” subjects compared to “unvaccinated” subjects, or if only found in “vaccinated” but not in “unvaccinated.”

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Decision Junction's avatar

The 803 subjects were unvaccinated and never had COVID, the 10 were completely healthy individuals with no health or cancer risks. The post-malignancies occurred within 12 months of being vaccinated.

To refute the methodological and interpretive critiques of the transcriptomic study titled “Synthetic mRNA Vaccines and Transcriptomic Dysregulation” (Catanzaro et al.), we must directly address each concern within the framework of the paper’s justifications, data structure, and scientific rationale, without denying legitimate limitations. Below is a structured rebuttal, combining empirical defense and clarification.

🔴 Critique 1: “Extremely Small Sample Size (n = 3 and n = 7 vs n = 803)”

✅ Rebuttal:

Biological signal strength > sample size: The 10 patients were clinically pre-screened, with no prior disease, genetic risk, or comorbidities, and presented synchronous onset of pathology within a defined window post-mRNA vaccine. This reduces heterogeneity, amplifying the signal-to-noise ratio in transcriptomic data.

Controls (n=803) were not randomly selected. They represent a pre-COVID, unvaccinated, and healthy population. This high baseline allows for confident identification of outlier transcriptional states, especially when:

NES (normalized enrichment scores) > 2.0

FDR < 0.001 for hallmark pathways

Preranked GSEA was deliberately chosen to stabilize interpretation despite n=3 and n=7. This method does not rely on group variance but on consistent gene ranking, which is valid in rare case analyses.

DESeq2 with apeglm shrinkage was employed to stabilize fold-change estimates and mitigate overdispersion due to small n.

Key point: These are not generalizable population stats, but focused molecular snapshots of outlier pathology. The goal is mechanistic insight, not epidemiology.

🟠 Critique 2: “No batch correction or demographic controls”

✅ Rebuttal:

All samples were processed at one centralized academic genomics center (UNT BioDiscovery Institute) with standardized protocols and same platform (NextSeq 550). Collection tubes, RNA kits, library prep kits, and sequencing runs were standardized.

Handling bias is minimized: All patients were enrolled through Neo7Bioscience, with same-day blood processing, eliminating major site-based confounders.

Demographics were intentionally homogenized (age 18–70, no major comorbidities). The post-vaccine cancer patients were low-risk individuals with no known cancer predisposition, reinforcing that transcriptomic shifts are not explained by age or disease burden.

🟠 Critique 3: “Unclear cancer definitions, timelines, or risk factors”

✅ Rebuttal:

The timeline of cancer emergence (<12 months post-injection) and lack of prior cancer risk are explicitly stated in the paper’s methods section .

All cancers were new-onset diagnoses, not relapses or progressions.

The study does not claim causality, but rather presents distinct transcriptomic signatures (e.g., cGAS–STING activation, epigenetic remodeling, MYC/p53 dysregulation) consistent with early oncogenesis or tumor-promoting shifts.

Peripheral blood RNA-seq is a legitimate noninvasive readout for systemic oncogenic stress and immune disruption, particularly when MYC targets, DNA methylation pathways, and ribosome biogenesis are enriched.

🟡 Critique 4: “GSEA is overinterpreted”

✅ Rebuttal:

Authors clearly define that GSEA indicates enrichment, not causality.

The pathway grouping (e.g., “Transcriptomic Instability”, “Proliferative Signaling”) is based on canonical MSigDB sets with high NES and low FDR, then clustered into higher-order biological themes for readability.

Such thematic grouping is common in systems biology and complements the granular data provided in Tables 1 and 2 .

🟡 Critique 5: “No technical or protein validation”

✅ Rebuttal:

The paper is transcriptomics-focused. Authors state that:

“These findings underscore the need for further clinical and proteomic validation” (p.14).

However, the internal cross-consistency (MYC, NMD, ribosome stress, cGAS-STING) across two different pathologies (AE and cancer) enhances biological credibility.

Supplementary materials and references (e.g., Boros et al., Patterson et al.) independently confirm persistent spike protein, ACE2 suppression, and mRNA fragments in circulation, supporting the transcriptomic mechanisms proposed.

🟡 Critique 6: “NES misinterpreted as FDR”

✅ Rebuttal:

The paper correctly distinguishes NES and FDR in the tables and figure legends.

If the text at any point implies NES as a false discovery metric, it would be a minor editorial oversight, not a methodological flaw.

All enrichment thresholds are defined as “NES > 1.5 and FDR < 0.25” per GSEA conventions.

🟢 On Strengths:

The use of STAR, Salmon, DESeq2 (with apeglm shrinkage), GSEA, and Cytoscape reflects rigorous pipeline design.

Sample selection criteria, centralized processing, and manual filtering of irrelevant gene sets all contribute to increased validity.

Conclusion

While the sample size is small and the study doesn’t claim population-level generalizability, the depth, reproducibility of patterns, and alignment with known adverse biology of spike protein and mRNA constructs justify the use of outlier transcriptomics to flag molecular risk. These findings open the door to precision surveillance, not statistical causation.

This is a mechanistic, hypothesis-generating research study—not a clinical trial—but its scientific integrity holds up under scrutiny.

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Hilary Butler's avatar

Okay, but shouldn't the article have clearly stated that 803 healthy control subjects were unvaccinated and never had COVID? Shouldn't the cancer cases have stated the vaccine type and batch numbers? Would any of your explanations have been necessary, if the article had all necessary details clearly defined?

When a person has to do the kind of refutation you have done above, it indicates that the study itself needs to be pulled, clarifications inserted, and then re-uploaded.

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Allie's avatar

I read this posting this AM after a night of no sleep, not feeling well. But I read it again and the summary report was not clear. I will download and read the original article, which we all should do. Thank you, Decision Junction for doing that for us. Your description of the subjects was very clear, unlike the summary posted here. My first thought was the very small sample size as you mentioned. It could be considered a pilot study. These lab analyses need to be done on more people to give further weight to the conclusions.

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Decision Junction's avatar

The 10 once health with no risk or cancer developed serious cancer within 12 months of mRNA vaccination. The 803 are healthy pre-covid and never vaccinated.

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Hilary Butler's avatar

Okay, so where in the paper, does it ACTUALLY say that those 803 healthy controls where healthy pre-covid and never vaccinated?

If that is so, then shouldn't that he stated right at the beginning?

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melinda field's avatar

agree

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Jason's avatar

America’s number one top pathologist, Dr Ryan Cole, literally explained this to us in 2020 and 2021. There’s nothing landmark or novel about these ‘new’ studies, if anything they could’ve warned us years ago and saved lives but chose to wait until it was “politically and socially more palatable to expose the truth and extreme dangers of this bio weapon” to the general public.

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John Fisgus's avatar

Yet the major medical associations are SUING the HHS to keep recommending this “vaccine” to pregnant women and children…. These are not physicians leading these associations, they’re sadistic murderers for hire by the pharmaceutical industry. What sick bastards… Why hasn’t RFK already pulled this poison off the market in the first place? I don’t know when, but there will be a day of reckoning for Fauci, Pfizer, Moderna.. and everyone else involved. At some point we’re gonna need Nuremberg style trials.

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Jo Hayman's avatar

Actually, it’s FAR past time to try the criminals who had any part of this blatant depopulation scheme, in a very public court and allow the millions of damaged people and the families of those murdered by the jabs, to be the juries and pass judgement/punishment on these demons. They deserve no less than the hideous deaths they have caused to innocent people around the world.

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Carol Taylor's avatar

This mRNA vaccine was all about depopulation! Bill Gates said in 2008 summit! "We have to depopulate, and we will do it with a vaccine" Dr Fauci was the partner in Crime with the other globalist!

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Brandon is not your bro's avatar

Last author on the paper is outstanding…. U of North Texas in Denton . https://neo7bioscience.com/about

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George's avatar

The Summing Up Thanks To Dr. J.J.Couey From Gigaohmbiological.com

1. Intramuscular injection is just a spectacularly dumb idea from the late 1800s. Cutaneous immunization works, just not always predicably. It is also painful and scars.

2. There was an anticipated rise in all-cause mortality (ACM) that remains and may even continue to increase in the future. This anticipated rise in ACM could have bankrupt many Western nations and is the biological signal being MANAGED with

manslaughter and lies. Many of these lies are told on social media by coordinated liars scripted to in turn promote or oppose other liars on the same script.

3. Modern RNA virology has also been used to strengthen and extend this Illusion. Claiming to find genetic signals in the wild, RNA virology then uses pure quantities of synthetic recombinant DNA or RNA TRANSFECTION in both cell cultures and animal models. This is fraud.

4. Coordinated liars fooled all of us into solving the Mystery of the Novel Virus. "Where did it come from? Who is responsible?" Participating in this Theater (even passively) coerced all of us into accepting several false premises, including that we were all in danger, and that we could be in danger again in the future.

5. RNA cannot be the basis for a pandemic because it has none of the special chemical characteristics that DNA supposedly has. When was the last DNA based pandemic? Gain of Function is a Mythology created by DOD+HHS to make an RNA pandemic biologically plausible. It is not.

6. These injections were actually old technologies-sometimes differentiated as TRANSFORMATION (adenovirus vectors, DNA) and TRANSFECTION (RNA)—that were just renamed and reformulated to be treated as new countermeasures, avoid regulation, and allow for the claiming of new intellectual property. This is fraud for which the PREP act emergency was a required moving part. Now the FDA will now be made irrelevant.

7. There is an irreducibly complex Background of genetic signals around us. A huge percentage but not all of these signals are related to bacteria and bacteriophages. The use of PCR in both virology and medicine make no effort to differentiate from this Background, using neither positive nor negative controls, as well as offering no reference scalar. The continued fraudulent use of PCR as a medical diagnostic creates a valuable medical remnant stream ideal for the Human Genome Project objectives. 8. The Health Freedom Movement can be seen as fake because of decades of failure to realize any of these Truths, especially #1. There are witting and unwitting participants. Ralph Baric, Peter Daszak, Paul Offit, Mary Holland, Andrew Wakefield, Polly Tommy, Vincent Racaniello, Pierre Kory, Robert Malone, and Robert F Kennedy are all part of One Malevolent Script. It is that bad.

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Tanya Quarterman's avatar

As of March 28, 2025, 9 million children had received the latest version of the COVID shot, but a month after this interview, @CDCgov stopped reporting this data.

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edward's avatar

The experimental jab produces a lengthy litany of serious side effects up to and including death as in bodily assault and murder. So where are the people in blue uniforms and the court CYSTem? Guess they are all ball cupping or kissing the hairy asses of demented bureauCRAP LPC meathead criminals. The stupid bastards go along with a corrupt government and ignore capital crimes committed by the damned CYSTem but harass drivers going one mile per hour over the speed limit. Keystone cops reappeared the day after turdie boy the slime minister was elected. They arrested peaceful protesters, stole 5.5 million in donations to the Freedom Trucker Heroes, trampled with their police horses an elderly disabled woman on her access scooter, and now the f*ckers in the court CYSTem want to jail two totally innocent leaders/heroes. Where are their criminal orders coming from? We all know. The courts are prejudicially biased and take marching orders from delusional fools in bureaucrapic positions from all places like the CanCUCKistan INhuman Blights Commission ASSWIPES. Right Sharon? McConnell? Tavarres? (SFOPP pigs in blue uniforms.) Your time to be exposed is shortly to come. Do not you damned fools know that the devil gets his dues and that all that is done in secret will be revealed? Your duplicity and lies, deceptions, bigotry and criminality was and is noted. How about you, the lying Gayla? Have not forgotten your lies and bigotry.

The whole excremental biomass of the LPC including turdo and now carnage and both ASSministrations need to be arrested, tried, and then stood in front of a concrete wall and executed by firing squad for murder by jab and treason. Wipe out these criminals to reduce globaloney. Maybe Greta Stunnedburg and Al Whore could preach at their funerals.

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edward's avatar

Where is justice? Where is Freedom? Where is Truth? People in blue uniforms are raping intoxicated women, and getting 400 grand to boot. Pigs are trampling elderly disabled women. Shooting dead elderly unarmed semi retired gunsmiths. Turdo and Carney need to be brought before a true Judge and sentenced to death for treason and murder.

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Hilary Butler's avatar

A very important question: 803 healthy control cohort?

Who is the healthy control cohort?

Were 400 vaccinated with mRNA jabs?

..... and 403 not-vaccinated?

Because that is how it should have been done.

This is the problem that we have with all these studies that look with MMR or any other vaccine. They never have an unvaccinated control group,

If the control cohort had 400 healthy vaccinated and 403 healthy unvaccinated, you could have very different genetic profiles in both groups.

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Scrub-Texas's avatar

Not enough studies on downstream aka those who are shed on, the blood and plasma supplies, genetic mutations from vaxed moms in the future. Guessing by the time the vax is taken off the market (pfft) even the unvaxxed are going to pay a heavy cost too - more reason to never forget and never forgive - tick tock

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NJ Election Advisor's avatar

It’s totally brutal. So much damaged to the unjabbed, unwilling victims.

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Scrub-Texas's avatar

Amen - First hand knowledge of brutal 28yo unvaxxed very healthy daughter returns to office with 10 double vaxed coworkers a few short weeks later in the hospital with what they thought was MS but was optic neuropathy lost some vision and distorted visions in both eyes. Vision back now has parimiso? Issues with smell and taste.

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