By Peter A. McCullough, MD, MPH
Heart failure is on the rise with the aging of the population and the superimposed effect of COVID-19 vaccination causing subclinical myopericarditis and contributing to the long-term risk of cardiomyopathy and heart failure.
Most of the body’s daily requirement for coenzyme Q10 (CoQ10) is produced within the body. Only a small amount of CoQ10 is ingested from food (typically 5 mg/day [5]). It is estimated that the daily requirement for CoQ10, from both endogenous bio-synthesis and food sources, is about 500 mg. This estimate serves as the justification for the size of the dosage (typically 300 mg/day) that is used in many clinical trial studies.
As we grow older, the ability of the body to synthesise its own CoQ10 decreases; optimal human bio-synthesis occurs in the mid-twenties, with a continual gradual decline in tissue levels thereafter [6]. In addition to the normal aging process, CoQ10 levels have also been shown to be depleted in a number of disorders, particularly heart disease [7].
