FOCAL POINTS (Courageous Discourse)

FOCAL POINTS (Courageous Discourse)

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FOCAL POINTS (Courageous Discourse)
FOCAL POINTS (Courageous Discourse)
NEW STUDY - Natural Compounds Outperform SSRIs in Treating Depression
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NEW STUDY - Natural Compounds Outperform SSRIs in Treating Depression

Massive meta-analysis of 192 trials and 44 compounds finds saffron, curcumin, and omega-3s outperform antidepressants across the board — without the side effects.

Nicolas Hulscher, MPH's avatar
Nicolas Hulscher, MPH
May 10, 2025
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FOCAL POINTS (Courageous Discourse)
FOCAL POINTS (Courageous Discourse)
NEW STUDY - Natural Compounds Outperform SSRIs in Treating Depression
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By Nicolas Hulscher, MPH

As U.S. depression rates hit historic highs, new evidence points toward a safer, more effective path forward.

A major meta-analysis published in Psychological Medicine evaluated 192 randomized controlled trials with over 17,000 patients, comparing 44 nutraceuticals against each other, placebo, and antidepressant drugs (ADT). The results are striking — and deeply relevant for millions seeking alternatives to dangerous pharmaceutical anti-depressants such as SSRIs.

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