Potential Health Risks of mRNA-Based Vaccine Platforms
Despite 30 Years of Development, Thousands of Patents, Basic Questions are Unanswered
By Peter A. McCullough, MD, MPH
My clinical practice is loaded with patients who took one or two vaccines early in 2021 and realized like most of us that the the mRNA products were not safe. A common question is: “doctor when does this shot get out of my body?”
Acevedo-Whitehouse and Bruno raise this point in a recent peer reviewed publication concerning the entire mRNA vaccine product pipeline.
Therapeutic applications of synthetic mRNA were proposed more than 30 years ago, and are currently the basis of one of the vaccine platforms used at a massive scale as part of the public health strategy to get COVID-19 under control. To date, there are no published studies on the biodistribution, cellular uptake, endosomal escape, translation rates, functional half-life and inactivation kinetics of synthetic mRNA, rates and duration of vaccine-induced antigen expression in different cell types. Furthermore, despite the assumption that there is no possibility of genomic integration of therapeutic synthetic mRNA, only one recent study has examined interactions between vaccine mRNA and the genome of transfected cells, and reported that an endogenous retrotransposon, LINE-1 is unsilenced following mRNA entry to the cell, leading to reverse transcription of full length vaccine mRNA sequences, and nuclear entry. This finding should be a major safety concern, given the possibility of synthetic mRNA-driven epigenetic and genomic modifications arising.
These are stunning revelations. I have called for a halt on mRNA research development until these fundamental questions can be answered. If synthetic mRNA cannot be broken down by the human body, there were be no way to shut off potentially dangerous antigens such as the Spike protein of SARS-CoV-2, Influenza virus hemagglutinin (HA), or any other toxin produced from the genetic code. To make matters worse, it appears that all of these proteins will be expressed on the cell surface and cause auto-immunity with any new mRNA vaccine. This alone is a show stopper for me in my practice. I am advising NO mRNA vaccines for my patients.
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Peter A. McCullough, MD, MPH
President, McCullough Foundation
As a veteran of bio pharmaceutical R&D, I understand the principles and practices of what’s sometimes called “rational drug design”, which is distinguished from the earliest examples of pharmaceuticals, often extracted natural products.
All medicines that aren’t natural products are designed, made and tested by humans. There is nothing in such a medical product that wasn’t chosen to be there.
Each element of the preparation has a purpose and nothing is there by chance.
Looking at these injections with the eye of someone experienced in the design process and also trained in mechanistic toxicology means I might have an almost uniquely fortunate set of skills and knowledge in answering this question:
“What was the designer of this product thinking & intending to happen, based on the choices that have evidently been made?”
I regret to say that I am certain that the intention was to injure, maim and kill recipients & also to reduce fertility of survivors.
One “mistake” might be tolerated by some, but it shouldn’t be. As Peter rightly observes here, causing the body to manufacture a non-self protein will, axiomatically, lead to our immune system attacking & killing every cell that takes part in this deathly pathway.
It doesn’t end there. Why pick spike protein? Any part of the alleged pathogen would suffice to raise an immune response (though any foreign protein will trigger fatal attacks on every cell responding to the “vaccine”). Picking spike made things worse, because analogous proteins are biologically active and toxic to blood, nerves and other tissues. This was well known.
Formulating these mRNA based products in lipid nano particles is particularly offensive.
Our cells object to foreign genetic material entering our cells, for reasons I hope are obvious. Cellular defences can be fooled if the genetic material is disguised & that’s what LNP does. It assists the product to travel everywhere in the body, including the heart, brain, developing foetus etc.
But I was stunned to learn that a 2012 review of these macromolecular carriers shared a property & that was that they all accumulate in the ovaries.
Anyone who thinks it’s unfortunate that they chose LNP surprises me.
Now recall they were desperate to jab pregnant women and even children. How many babies in utero were killed? How many girls & women will later realise they’re infertile?
Now notice that where the basic technology was shared, every important design decision was also shared. There are no important differences between Pfizer / BioNTech & Moderna’s “vaccine”, only dose.
I have been a team member or leader of dozens of teams engaged in directed research seeking clinical drug candidates.
I know with certainty that “Mistakes Were Not Made”. These design decisions were all deliberate. I haven’t any doubt about that. It’s in my testimony to all audiences including for the law.
Please don’t accept any more of these intentionally toxic products.
Also, it’s very important that, frightening though this realisation is, we must use it to wake up more people in order to oppose the thoroughly malign, I would say diabolical, plans of those who planned this.
Best wishes
Dr Mike Yeadon
Peter, please would you consider pinning this comment? Thanks.
This is damn scary stuff! The paragraph this is in: ". . . To date, there are no published studies on the biodistribution, cellular uptake, endosomal escape . . . " etc.
Quite creeped me out!
It is no exaggeration to say that this bioweapon attack on humanity is the most egregious Crime Against Humanity ever committed!!!!