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Blondie237's avatar

I've been taking a product that contains Nattokinese for years (way before cvd) for endometriosis pain. It works amazingly well. In fact, it is the only thing that reduced the pain enough so I could work, and it does not leave me feeling loopy like the pain meds that docs prescribed. And I'm not having to have surgeries every couple of years to remove endo. I'm glad to know it has other benefits as well.

Michele Proano Kressin's avatar

I'm so glad you found something that works!

Collapse Podcast's avatar

this is a blessing to read. Thank you.

Stephen Thompson's avatar

Have you researched a carnivore diet to see if that helps also ?

Blondie237's avatar

Stephen, if you are asking if it woul help with endo pain, the answer is no. In fact, a long time ago I read that cutting back on meat would help Endo pain. I think I read this in one of Dr. John Lee's books on bioidentical Progesterone. Endo is caused by an unbalance in estrogen and progesterone..... too much estrogen in relation to progesterone.

Most meat these days has all kinds of hormones in it. But also meat moves slower through the digestive tract vs. high fiber foods. While meat is sitting in the intestines digesting, the body has time to re-absorb wastes including excess hormones etc that have been collected a long the way. High fiber foods move more quickly, so the hormones in the wastes don't have time to be reabsorbed by the body. I eliminated beef and pork first and it helped with pain. So, over the years, I eliminated all meat. Haven't had any in decades.

Alecia Lynn's avatar

Thank you for sharing information. Even though I am too poor to see Dr. McCulloigh, I am smart enough to help myself with your excellent research. I appreciate your work.

Please don't stop.

franco nocentini's avatar

In my personal experience, after a very long personal use of nattokinase for almost 3 years with doses of 2000, 4000, 8000, 10000 FU tested progressively, its effectiveness on previous symptoms such as persistent muscle fatigue for over 15 months, mild, apparently random tachycardia from 55 to 75 bpm at rest which only sometimes seem to be attributable to subsequent states after fatigue, for example after 8-10 km of walking in the hills, together with other symptoms such as slight variations in minimum and maximum blood pressure of 10 and 15 points respectively and a feeling of respiratory failure or much more worrying symptoms attributable to angina, here the reduction of all this does not seem to be attributable to the dose of nattokinase, I do not seem to have a clear correlation between the nattokinase taken and a reduction in symptoms.

Another positive effect, however, I don't know how much is attributable to the dose, but with high doses greater than or equal to 4000 FU, in about 2 years you can clearly see a reduction in the protruding veins, both on the backs of the hands and feet, or if you cut yourself, you can clearly see your blood is more liquid, that is, less viscous.

That's why I continued taking it, now I use it steadily at a dose of about 4000 + 4000 FU per day, especially given the effect on the blood, even without significant improvements in my symptoms. I thought that nattokinase could contribute much more if I took it in combination with other supplements. In fact, I saw improvements, albeit very slowly, with great satisfaction, combining it with Bromelain, N-acetyl cysteine, Curcumin, Vitamin C, Astragalus, and Cordyceps, which I am now reducing, but only slightly, because in the last 3 months the improvements are a little less noticeable, I think it's due to the effect of the heat.

an inverse dose-dependent effect of nattokinase is undoubtedly the decrease in its efficacy over time against night cramps, which however, whatever the dose, remain much less severe,

Rick Zammuto's avatar

I do most of them everyday for years; they eliminate many other problems!

Anonymous's avatar

I’v had poor heinous return in both lower legs for about 7 years manifesting as swollen ankles and swelling above sock compression lines mostly. Left leg was worse, compression socks did help but problem persisted. My elderly father had to have emergency surgery on his left leg due to a clogged artery behind the left knee. Almost lost his left foot.

So, about three months ago my left knee swole up to almost twice normal size in about a day or so. Obviously painful and quite different than the swelling due to poor heinous return and alarming as we as debilitating.

I thought about going to a vascular surgeon but didn’t want to get involved in the money oriented medical system if I could avoid it and having read about the benefits of nattokinase and bromelain I ordered some and began taking it orally, about 6000 units of nattokinase (Now Supplements) and the recommended dosage of bromelain, to which I added earnest believing prayer to The Great Physician.

To my considerable surprise and delight, in about 4-6 weeks there was a rapid reduction in swelling to near normal size of the knee comparing it to the other (right) knee. Over about another week there was continued reduction in swelling to normal size and all pain is gone.

In addition the swelling at sock line on both legs has stopped.

I cannot help but conclude the nattokinase and bromelain substantially dissolved clogged veins/arteries in both legs restoring normal or near normal blood flow. I do take DMSO orally and had been taking it when the knee swelling occurred so it alone neither prevented, nor resolved , the problem and only the nattokinase /bromelain were added to my regimen prior to this almost miraculous reversal of swelling in the left knee.

I continue to take both as I suspect due to my father’s case that I am genetically predisposed to such clotting. I eat a strict Mediterranean diet and have done so for years prior to this incident and my lipid numbers on blood work are all normal.

I’m 76 years old and pay attention to my health, and don’t expect someone else to fix me, especially one of the money hungry Drs trained allopathiclly in algorithm medicine based on big pharma’s “pill for symptoms “ but forget the cure” philosophy.

Thank god we have a few honest Drs around who are willing to learn beyond their original training and recognize its faults as well as its good aspects: A Midwestern Doctor is one of the best I have found in addition to Dr McCullough. No one has all the answers except the Great Physician, and only He can or will “one into all the Truth”.

Thank you Nic, for publishing this information so we can stay informed and take care of the body He gave us in order to serve Him better.

Jacob

To my surprise, within about

John Day MD's avatar

12,000 FU/d of nattokinase is easy to source as 3X 4000 FU capsules.

It is the approximation-in-practice of the 10,800 cardiac & plaque dose.

I have been advising this dose to people for whom it is appropriate for about 6 years, and it is well tolerated.

One patient had a near miraculous recovery from long-COVID/Vaxx and pulmonary emboli on nattokinase, high dose vitamin-D and little else. She got off multiple other meds.

John's avatar

I've been taking it for years now, but apparently at an ineffective dose. Time to find a stronger dose...it won't be from the good doctor, he's out of my price range.

LeaAnn Rosen's avatar

I must say that I am shocked at how much Dr McCullough is charging for Ivermectin and Mebenzedal. Just get the animal versions. I have lost a lot of respect for him because of this.

RLM's avatar

If you want an American product, TWC sells it. If you want an Indian product, go to alldaychemist.com.

jsinton's avatar

Actually it's quite reasonable considering the pill strength. Animal stuff actually cost more per mg.

edie gormay's avatar

I trust TWC over other brands: be sure you are getting the quality you need in other brands

sandy's avatar

alldaychemist.com previously recommended by Dr. Ardis. I do not know whether or not he is still recommending it.

JB's avatar

What about Lumbrokinase? I believe this does a better job than Nattokinase. Yes? But Lumbrokinase is more expensive than Nattokinase and you want to increase your spread.

In addition, I also know you work with McCullough and are probably shilling for Nattokinase bec he has his Spike product made into a tablet now and I've been getting an email a day to buy it. I dont' like tablets bec they are not very bioavailable. Why he put his big cure into a tablet is beyond me; probably it was more cost-effective, albeit, not bio-effective. He's just like Big Pharma, only on a lesser scale. And then to charge $539.00 for a formulation of Ivermectin and Mebendazole? Wow, talk about price gouging to the sick and dying. That should be criminal. Those 2 meds are dirt cheap. Yeah, I know it costs money to manufacture the pills, but the spread there is massive. Shame on him. It's never enough. It's never enough. What a way to live.

Barbara Johnston's avatar

I’m wondering too about the very high prices on Dr McCullough’s site? After his great work trying to save us during the Plandemic, why is he keeping his products out of reach financially for most people? I got IVM for a fraction of his cost during that dark time (thank God), but now it’s inaccessible. Why?

JB's avatar

He's doing the same thing Big Pharma does, which is price gouging bec he knows people will pay any price for a cure. Again, shame on him. He will answer to God, if he still believes in Him. Once people achieve fame and fortune, they forget about God and giving Him the glory. Oh well. We pray for him...

RLM's avatar

Yes, expensive. BUT, he lost his job, his journal, and nearly lost his career. While I think his products are a little too expensive, he is doing great work informing us about health conditions that plague millions. Part of the price in any purchase goes to continued support for research on behalf of those millions of medical orphans who have been abandoned by the government-pharma coalition to protect the rich and powerful. Insurance companies and local clinicians will never provide treatments for long covid or 'long vax.'

EGS's avatar

Yes, I’ve thought the same.

I’d like to hear about his costs (research, etc etc)? Prices seem to be increasing, dosages decreasing. It’s ALWAYS about the dose! Glad I bought extra supplies two years ago KNOWING that this seems to happen everytime...

User's avatar
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Sep 26
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JB's avatar

Right? I get mine from outside the country. Same same.

Eye-of-Agamotto's avatar

Same. I started doing this years ago when the research first starting coming out from other sources who I had learned to trust. The process taught me how to source peptides too. Not too long ago, I stunned someone who was buying the same type of 2 peptides I was using, at nearly 10x the price I was, from her "trusted' Dr. That opened her eyes on many levels and over the course of several conversations, discovered I'm not so crazy.

I won't go so far as to claim McC is price gouging, IMO he is simply playing to market dynamics he's in. Not everyone is like you and me and willing to invest the time and research to investigate other sources.

The sad fact of the matter is, the US market is the most exploited one, with the highest prices, in the world, especially for anything related to health. And in large part, that necessity is driven by how toxic our food supply has become.

JB's avatar

I agree. I recently learned of peptides and am intetested in using them on my husband, who is 86 and has dementia caused by concussions and epilepsy caused by a medically-induced brain bleed. The seizures have abated since I have started chelation and H2O2 infusions on him. The peace of mind is priceless. What do you think peptides can do for him? And what type of peptides, specifically? Thank you. (My avatar is a pic of my uncle from the 70s. LOL)

JB's avatar

How do you source peptides? Where does one get them? Seems to be more info "they" don't want us to have. Tyia

RLM's avatar
Sep 26Edited

My doctor recently told me, in his darkest tone, that animal IVM is differently formulated than human, and is bad for humans. Since there were people who bought IVM from Tractor Supply and similar, divided the container into the correct amount for their weight, and got it down somehow (applesauce? smoothies? who knows?) and they all remained quite healthy, I have two theories. One: the medical estab. is misinforming doctors. Two: the FDA is requiring IVM makers to include an ingredient that is toxic to humans.

Anybody know? Speak up!

JB's avatar

Idk

Peanut butter is another choice of making the medicine go down.

I have read that animal grade is not as pure as pharmaceutical grade mixtures, meant for humans. The animal grade formulas are less expensive, yet include more impurities, say like heavy metals, and other undesirable chemicals the manufacturer has deemed to be not fatal if the animal ingests them. Not too deleterious either but not too good for people.

I have taken animal grade meds for many years, simply to save time going to a doctor for a prescription if I have what I think I need on hand for the animals - and so do many people I know.

I'm not sure about IVM makers including a toxic human ingredient. I doubt it. I think the doctors have not studied it and do not want to be liable for talking about it or prescribing it, so they just nix it across the board. They do the same with DMSO. DMSO is a miracle drug and they do not want it around. Too bad. The cat is out of the bag, the horse has left the barn, and so has Elvis. I hope they have saved their money, because they will be obsolete as doctors in no time flat. Maybe they can use their prescription pads for lighting a fire.

User's avatar
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Sep 30
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JB's avatar

It’s not expensive. You have to know where to get it, like anything else in this life.

RLM's avatar

? Is a tablet necessarily less bioavailable than powder in capsules?

JB's avatar

I have heard that when cleaning outhouses, the "honey dippers" (outhouse cleaners) find small, hard little balls at the bottom. These were found to be partially-digested vitamin tablets. You decide...

Laura G's avatar

Is Toku providing the same benefit? It's not soybased but claims natto 10.5fu

Julie K's avatar

I use Lumbrokinase since we are allergic to soy. Seems to work. Might even be more potent 🤷‍♀️

Rick Zammuto's avatar

It is equivalent to 100 doses of 2000 FU.

Barbara Johnston's avatar

What is Toku? I’m trying to stay away from soybean-which seems to be in everything

Douglas's avatar

You can make natto with chickpeas which apparently has an equivalent and even higher nutrient profile. Supplemental forms using fermented chickpeas are also available, Sayer-ji has one on the market, also Sports Research uses chickpeas for their K2

RLM's avatar

Toku is a brand. See Amazon.

Deanna Kline's avatar

Will never forget him crying on video when warning us in early ‘21.. of course soon censored.

carol's avatar

Amazing. Thank you for sharing info

jsinton's avatar

What I have found using Ultimate Spike detox is that is suppresses the nanobots and the clots while in vivo, but put some blood on a slide and it comes right back and the blood gets transformed to plastic and does not dry out as blood should. I have to use additional methods to kill the plastic. The other problem is the hard stuff in your head, where this accumulates most, is VERY hard to remove. But there are ways I'm working on to get that too. My two cents.

RLM's avatar

My understanding is that nattokinase works via fibrinolysis (i.e., removing clots from blood vessels), and that NAC, esp. the augmented form, ' helps detach the spike protein from ACE2 receptors, facilitating its natural excretion from the body.' One study said that NAC needs bromelain to be most effective.

marta's avatar

Thank you Nicholas for this great information. I want to ask you where do you list the references for these results? Where do you list the studies? I'd be interested in seeing those. Thank you

Steven Slevin's avatar

Who carries out a spike protein level test??

JB's avatar

You can get it done with a blood test. Go to a naturopath and they know which test to order.

You can also find out by doing a D-Dimer test and a heart test, although Idk which one at the moment. Find someone who is on your side concerning the shots and they will know.

Mike Fein's avatar

LabCorp is now located in many Walgreens locations. Register online with Labcorp, cough up the $79 for the test. See Covid 19 Antibody Test. They are very good regarding your time, and their phlebotomists are also very good. I started testing in September of 2025, and test quarterly. If Doc Pete is going to start efficacy studies, my biggest question is will the results remain arithmetic, meaning in 42 months I go to zero antibodies, or does it go logarithmic at some point. This assumes I do not get recontaminated. Test results:

9/25. 19389

12/25. 16792

3/26. 18066

6/26. 15929

9/26. 14924

So with a year's worth of data, and full McCullough protocol, that is 4400 antibody spike antibody drop in one year. That yields a zero number in 40 months. The trend, despite the anomaly, is still down.

One question: Why did Pete drop the original breakover at 15,000? Compare the original antibody pie chart, vs his recent revision. Best wishes to you and others fighting the heightened cancer risks, and associated poisonings.

RLM's avatar

What do you mean by 'original breakover'? And was your antibody level ever higher than 19.3K? And are you also taking, say, Vit. C, D3, and/or NAC? I'm guessing at any rate, that NAC might also reduce antibody levels (based on other research not included in this study).

Mike Fein's avatar

Good questions!

When Dr Pete created the original detox protocol, He had different levels of risk for antibody levels, (from memory):

Very low-level past exposure was <1000U/ml

moderate exposure was >1000-5000U/ml

high was 10000-15000

very high was 15,000-20000.

Please locate a paper, likely from 2024, regarding these numbers.

In his latest missive, "The Spike Protein Effect" published 8/26/26, this changed.

low still <1000

moderate 1000-5000

high persistent spike protein 5000-10000

very high risk was 10000-25000

And I get it, the risk values change as more data becomes available. So the "breakover" from super high to just high at 15000 has changed with new data, and my thought that my risk category had dropped, is incorrect. I indeed take C,D3, and other supplements, but with my kidney stone issues, I avoid NAC. Thanks again for great questions and your interest in my numbers.🤝

RLM's avatar
Sep 23Edited

Within the past 12 mos. he interviewed an MD who, with only 10K spike protein antibodies, was still debilitated from the vaccine. Perhaps that was the reason for the change. At any rate, I had >19k results from that Roche spike protein antibody test in 2022 -- and felt great. But then after several more bouts of covid, test results rose to unmeasurable levels at >25K, and symptoms have destroyed 75% of normal daily productivity level. So your numbers give some hope, though a switch to lumbrokinase might be in order, as it is more powerful than natto. As for NAC, the commonly mentioned side effect is GI tract issues, not kidney stones, so you are surprising me. Anyway, many thanks for your kind and informative reply. Here's to good health for all victims of the mRNA shot.

Mike Fein's avatar

The 19.3K was a base line when I started the Pete Protocol.

Allie's avatar

LabCorp can run a spike antigen test that you can order for yourself. There is a company in Germany that directly analyzes spike protein.

Julie K's avatar

My integrative doctor did mine

Steven Robles's avatar

My Doctors don’t want me on Natokinase because they have me on two blood thinners. My amyloid clots have blocked of five arteries so far. Three stents, a fem fem bypass and the SFA completely clotted off while having the bypass procedure. My last spike protein level was over 26000. What to do? Severe Claudication really sucks.

RLM's avatar

Ask about NAC, esp. augmented NAC, + bromelain. Remember that doctors don't want you interfering with their treatment, but OTOH, we don't want you to die from internal bleeding. You might also ask about serropeptase and/or lumbrokinase. The problem with what you are saying is that natto helps with fibrinolysis, which would reduce/break up the blood clots. Their approach thins the blood and leaves the clots in place, right?. Tough call.

Steven Robles's avatar

I do take NAC and Glutathione in liposomal form. Seeing another Vascular surgeon soon since being let go from Kaiser Permanente

RLM's avatar

Here is a very short list of possibly useful information.

This site is the standard 'no proof of anything' MD advice, but still worth looking at because it considers DOSAGE SAFETY: https://drjessesantiano.com/how-to-dose-nattokinase-bromelain-and-nac/

This study (Brazilian/Australian) shows evidence that bromelain-Nac cleaves the spike protein: https://www.nature.com/articles/s41598-025-92242-y.pdf

"The combination of Bromelain and Acetylcysteine (BromAc) synergistically inactivates SARS-CoV-2" French/Australian study. https://www.biorxiv.org/content/10.1101/2020.09.07.286906v2.full.pdf

To date, there is no study that PROVES anything useful for vax victims. Unless there is a huge public outcry, it will never happen. So vax and long covid victims have to take whatever action they can on their own behalf, because the CDC isn't going to come on a white horse and save them.

I wish you a full recovery, health, peace, and freedom. So sorry you have this situation to endure. Best wishes.

James McCartney's avatar

They are trying to kill You. Get It

James McCartney's avatar

If you've got Nattokinknace, where did you get it. Your bloody lucky. I'll have yours

RLM's avatar

Try Walmart or Amazon. Supposedly good brands are Nutricost, Pure Encapsulations, and Life Extension.

James McCartney's avatar

If you've got Nattokinknace, where did you get it. Your bloody lucky. I'll have yours

Dottie Wottie's avatar

I used to make my own natto but ferment it with a different bean such as garbanzo beans. It isn’t the best tasting, but it’s good for you. I’d like to know how the food compares to a capsule.

Trevor's avatar

BIOWEAPON DEFENSE.