Ensitrelvir stops SARS-CoV-2 in hours. Boosters take weeks for theoretical protection. Why are we still pretending fall boosters matter more than availability of a direct antiviral drug?
I will see how it works and after 10 years I “might” consider it. I do not trust clinical trial evaluations any more. They are slanted and we really don’t know the truth of how they are performed and what their methods prove. So many times we are lied to. Very skeptical.
Has this pill proven to be a more effective prophylactic for covid than Ivermectin or Hydroxychloroquine, which have much better established safety profiles?
Regardless of whether this anti-viral is effective or not, an mRNA "vaccine"/booster should never be an option. These often damaging/lethal products should have been taken off the market years ago, as Dr. McCullough himself has said numerous times. Our bodies are NOT supposed to be producing a foreign protein!
Dr. McCullough — as someone in myself who's spent a large amount of time studying clinical trials, and the propaganda that goes into them, I caution against any pharmaceutical; especially antivirals. I've written on how these trials are fudged so drugs can get approved, only to have dangerous side effects later on down the line. Tamiflu comes to mind. Here's that piece, if anyone is interested, but stay away from pharmaceuticals: https://unorthodoxy.substack.com/p/the-power-of-the-clinical-trial-big
Synthetic drugs are for profit, and are sure to cause more toxicity and problems. There are better ways to stay healthy naturally, but there's no money in that. When will we ever learn?
You don't have to wait 10 years to have a good idea if it's ok. We knew the vaccine was not after 1 (if not months). I have a lot of trust in Dr. McCullough. For sure more than the pharmaceutical companies. The opposite of extreme faith is extreme skepticism and I think it is wise to avoid both. And an antiviral does NOT make your body produce spike protein indefinitely. You cannot begin to compare. My preference is also natural means, but if it's a choice between an antiviral which like all drugs - including aspirin - have side effects, or taking a mRNA vaccine, there is no question.
The Big pHarma owned medical journals are at it again. A study was published saying that ensitrelvir had no benefit for patients hospitalized with COVID. (Baker JV, Siegel L, Losso M, et al; for the STRIVE Study Team. Ensitrelvir for the treatment of hospitalized adults with COVID-19: an international phase 3 randomized placebo-controlled trial. Clin Infect Dis. Published online April 22, 2026. doi:10.1093/cid/ciag272). So patients were enrolled up to 14 days after symptom onset (way too long a delay) and they also received standard care, including remdesivir. Another study designed to fail. These authors need to be called out for their shoddy work.
What's happened here from the man who put his career on the line, alerting all to the dangers of the Covid jab and demanding over and over again that it be taken off the market? And now this milk-toast criticism of the experimental jabs as having waning effectiveness. How about long-term injuries and death? I'm amazed.
Was this new antiviral developed, tested in or manufactured using cell cultures derived from the organ harvesting of preborn babies during an abortion?
While we are encouraged by Dr. Mac and Courageous discourse’s work and that the good doctors stay in their lanes of finding cures for malaise and demise, we must be cognizant of the much larger picture of control that deny’s individual sovereignty.
The people making a product of this magnitude (GOF virology) are of low moral and ethical character, that is they may be otherwise “nice” people, but their reason has been skewed ether because they have been captured by complicity, blackmail, or greed, all rooted in their own fear, so what they say is irrelevant, especially when using the mantra of “for the good of all” of every totalitarian regime that destroy’s independence. All that it takes is like minded ilk born of a mentality that fulfills the nefarious qualifications to join a cabal
Fauci was not the ring leader but a person well versed in working the levers large and small between academia and bureaucratic funding regulation-ship, and understanding which levers (media) to pull and when to begin the occurrence based on previous experience of manipulating panic (AID’s and SARS). But the perps of one cabal may not even realize they are part of a larger plan to test the global lock down power of a much larger mindset of global control that expunges all sovereignty, not just body sovereignty.
Once a person, especially an unelected person wields that power it can metastasize at the speed of panic and chaos. The uniparty under the Democrat Party banner know that they and their 90% Democrat voting academic union (teachers K-12), and bureaucratic (regulatory) system has been proven untrustworthy and of despicable intolerant character of projection and inversion, constantly moving the goal posts to avoid responsibility, one would think the next question of accountability would be asked, why?
All they have is “get Trump”, 24/7 for twelve years and counting, officially, and their bag of liberal ism’s.
Yet half the people propagandized by the cabals of the Leftist globalists cannot square the circle of “why” this President is maintained to be the villain and what that means on a grand scale. That is because we are in a war for America’s soul, and the first thing trained to lose in war is innocence, to muddle the line between good and evil.
Remember, we were forced by the mantra to allow loved ones to suffocate to death alone after spending their lives building family, without goodby’s or opportunity to expound on their experiences because we wanted to be good people following the rules, but most refused to believe the “conspiracy theory” that the stew was already cooked, all Fauci need do is add pinches of fear porn out front at the podium.
It reminds me of one of the first pictures of Fauci at the SIT-REP microphone, President Trump off to his Left with a sideward glance of Fauci that clearly shows expression of distrust, but the “experts” were more assertive and aggressive than the caution of the good doctors and the Democrat owned media held the gun at both sides of the Presidents head.
If this is allowed to continue to be promulgated as a facet or part, a plan to re-construct, or “Reset” the human genome under the cover of a much larger plan to facilitate conspiracy to expunge independence and body sovereignty in all sovereign countries, the framework of global control, then neither Fauci nor Epstine matter much. They are but little puppets in comparison to the big Eurasian Monarchial bloodlines that manipulate the FED, London World Banking system and Lloyds of London insurers, not only still alive across Eurasian countries under the guise of DAVOS, WEF, WHO, WBS, NATO etc., but in the process of destroying their own countries’ identity.
This is why the globalist Oligarchy, “foreign and domestic” (enemy’s) that have been used to control the culture and economy’s of totalitarian countries for decades, and why they now again rely on their minions of the Democrat uniparty vehicle to invert the script to attack all “wealthy” Oligarchy as villains to point the finger at President Trump. Their newest media narrative from Leftist Communists minions like Bernie Sanders, AOC, and candidates with extreme Nazi tattoo’s and new comers of Jew and Christian hatred while promoting Islam-ism.
Please understand that these entities are proven to have covertly colluded over eight decades since post Korean War to command globalist control by regional sectors, one of which is meant for America to be a part of (North Western), by usurping and relinquishing America’s primary authority of the Constitution to hand control to unelected committees from afar, especially beginning with the NATO/WHO authority who are all in with America’s great majority “having nothing and being happy”. That’s how important expunging body sovereignty through a Socialist lens of fake caring “for the good of all” is to the main plan to take it all.
That was the plan until 2016 (45), and 2024 (47), and why they/them have thrown everything they have at him, five assassination attempts, and threaten the current administration if the deep State embedded tic’s of Democrat academia “unionized” (teachers) and bureaucratic useful idiots get back in power.
Normies prefer to push back on “conspiracy theories” because it threatens their sanctuary mindsets of busying themselves enough to be vulnerability to propaganda.
Half want Fauci hung, and half want amnesty because they need to feel “charitable”, they say, “he didn’t mean it” in a culture of defunding police, open jail cells, open borders, and media’s intentional non description of perp’s, and the collective cabals of globalist perps are counting on it.
Dr. McCullough — the Hayden et al. trial's primary endpoint is "symptomatic PCR-confirmed COVID-19" — a 67% reduction in signal-positive cases at a chosen Ct.
Sasha L's argument about EUA consent under 21 USC 360bbb-3(k) prompted me to think about what sits underneath it: PCR detects an amplification signal at an operator-chosen cycle threshold, not the identity of a virion. Western blot reads a molecular-weight band at a chosen kilodalton value. ELISA reads antibody reactivity at a chosen dilution. These are measurements of properties, not of identity. A trial endpoint built on them is reporting threshold-positive cases — which is a different claim than a reduction in disease.
I will see how it works and after 10 years I “might” consider it. I do not trust clinical trial evaluations any more. They are slanted and we really don’t know the truth of how they are performed and what their methods prove. So many times we are lied to. Very skeptical.
Has this pill proven to be a more effective prophylactic for covid than Ivermectin or Hydroxychloroquine, which have much better established safety profiles?
Regardless of whether this anti-viral is effective or not, an mRNA "vaccine"/booster should never be an option. These often damaging/lethal products should have been taken off the market years ago, as Dr. McCullough himself has said numerous times. Our bodies are NOT supposed to be producing a foreign protein!
Dr. McCullough — as someone in myself who's spent a large amount of time studying clinical trials, and the propaganda that goes into them, I caution against any pharmaceutical; especially antivirals. I've written on how these trials are fudged so drugs can get approved, only to have dangerous side effects later on down the line. Tamiflu comes to mind. Here's that piece, if anyone is interested, but stay away from pharmaceuticals: https://unorthodoxy.substack.com/p/the-power-of-the-clinical-trial-big
For children over 6 - who are at essentially 0 risk of harm. Another revenue stream for evil pediatricians?
Synthetic drugs are for profit, and are sure to cause more toxicity and problems. There are better ways to stay healthy naturally, but there's no money in that. When will we ever learn?
You don't have to wait 10 years to have a good idea if it's ok. We knew the vaccine was not after 1 (if not months). I have a lot of trust in Dr. McCullough. For sure more than the pharmaceutical companies. The opposite of extreme faith is extreme skepticism and I think it is wise to avoid both. And an antiviral does NOT make your body produce spike protein indefinitely. You cannot begin to compare. My preference is also natural means, but if it's a choice between an antiviral which like all drugs - including aspirin - have side effects, or taking a mRNA vaccine, there is no question.
The non-diagnostic PCR again?
Read my lips: EUA countermeasures and the 2005 Prep Act...
The Big pHarma owned medical journals are at it again. A study was published saying that ensitrelvir had no benefit for patients hospitalized with COVID. (Baker JV, Siegel L, Losso M, et al; for the STRIVE Study Team. Ensitrelvir for the treatment of hospitalized adults with COVID-19: an international phase 3 randomized placebo-controlled trial. Clin Infect Dis. Published online April 22, 2026. doi:10.1093/cid/ciag272). So patients were enrolled up to 14 days after symptom onset (way too long a delay) and they also received standard care, including remdesivir. Another study designed to fail. These authors need to be called out for their shoddy work.
What's happened here from the man who put his career on the line, alerting all to the dangers of the Covid jab and demanding over and over again that it be taken off the market? And now this milk-toast criticism of the experimental jabs as having waning effectiveness. How about long-term injuries and death? I'm amazed.
Was this new antiviral developed, tested in or manufactured using cell cultures derived from the organ harvesting of preborn babies during an abortion?
While we are encouraged by Dr. Mac and Courageous discourse’s work and that the good doctors stay in their lanes of finding cures for malaise and demise, we must be cognizant of the much larger picture of control that deny’s individual sovereignty.
The people making a product of this magnitude (GOF virology) are of low moral and ethical character, that is they may be otherwise “nice” people, but their reason has been skewed ether because they have been captured by complicity, blackmail, or greed, all rooted in their own fear, so what they say is irrelevant, especially when using the mantra of “for the good of all” of every totalitarian regime that destroy’s independence. All that it takes is like minded ilk born of a mentality that fulfills the nefarious qualifications to join a cabal
Fauci was not the ring leader but a person well versed in working the levers large and small between academia and bureaucratic funding regulation-ship, and understanding which levers (media) to pull and when to begin the occurrence based on previous experience of manipulating panic (AID’s and SARS). But the perps of one cabal may not even realize they are part of a larger plan to test the global lock down power of a much larger mindset of global control that expunges all sovereignty, not just body sovereignty.
Once a person, especially an unelected person wields that power it can metastasize at the speed of panic and chaos. The uniparty under the Democrat Party banner know that they and their 90% Democrat voting academic union (teachers K-12), and bureaucratic (regulatory) system has been proven untrustworthy and of despicable intolerant character of projection and inversion, constantly moving the goal posts to avoid responsibility, one would think the next question of accountability would be asked, why?
All they have is “get Trump”, 24/7 for twelve years and counting, officially, and their bag of liberal ism’s.
Yet half the people propagandized by the cabals of the Leftist globalists cannot square the circle of “why” this President is maintained to be the villain and what that means on a grand scale. That is because we are in a war for America’s soul, and the first thing trained to lose in war is innocence, to muddle the line between good and evil.
Remember, we were forced by the mantra to allow loved ones to suffocate to death alone after spending their lives building family, without goodby’s or opportunity to expound on their experiences because we wanted to be good people following the rules, but most refused to believe the “conspiracy theory” that the stew was already cooked, all Fauci need do is add pinches of fear porn out front at the podium.
It reminds me of one of the first pictures of Fauci at the SIT-REP microphone, President Trump off to his Left with a sideward glance of Fauci that clearly shows expression of distrust, but the “experts” were more assertive and aggressive than the caution of the good doctors and the Democrat owned media held the gun at both sides of the Presidents head.
If this is allowed to continue to be promulgated as a facet or part, a plan to re-construct, or “Reset” the human genome under the cover of a much larger plan to facilitate conspiracy to expunge independence and body sovereignty in all sovereign countries, the framework of global control, then neither Fauci nor Epstine matter much. They are but little puppets in comparison to the big Eurasian Monarchial bloodlines that manipulate the FED, London World Banking system and Lloyds of London insurers, not only still alive across Eurasian countries under the guise of DAVOS, WEF, WHO, WBS, NATO etc., but in the process of destroying their own countries’ identity.
This is why the globalist Oligarchy, “foreign and domestic” (enemy’s) that have been used to control the culture and economy’s of totalitarian countries for decades, and why they now again rely on their minions of the Democrat uniparty vehicle to invert the script to attack all “wealthy” Oligarchy as villains to point the finger at President Trump. Their newest media narrative from Leftist Communists minions like Bernie Sanders, AOC, and candidates with extreme Nazi tattoo’s and new comers of Jew and Christian hatred while promoting Islam-ism.
Please understand that these entities are proven to have covertly colluded over eight decades since post Korean War to command globalist control by regional sectors, one of which is meant for America to be a part of (North Western), by usurping and relinquishing America’s primary authority of the Constitution to hand control to unelected committees from afar, especially beginning with the NATO/WHO authority who are all in with America’s great majority “having nothing and being happy”. That’s how important expunging body sovereignty through a Socialist lens of fake caring “for the good of all” is to the main plan to take it all.
That was the plan until 2016 (45), and 2024 (47), and why they/them have thrown everything they have at him, five assassination attempts, and threaten the current administration if the deep State embedded tic’s of Democrat academia “unionized” (teachers) and bureaucratic useful idiots get back in power.
Normies prefer to push back on “conspiracy theories” because it threatens their sanctuary mindsets of busying themselves enough to be vulnerability to propaganda.
Half want Fauci hung, and half want amnesty because they need to feel “charitable”, they say, “he didn’t mean it” in a culture of defunding police, open jail cells, open borders, and media’s intentional non description of perp’s, and the collective cabals of globalist perps are counting on it.
Dr. McCullough — the Hayden et al. trial's primary endpoint is "symptomatic PCR-confirmed COVID-19" — a 67% reduction in signal-positive cases at a chosen Ct.
Sasha L's argument about EUA consent under 21 USC 360bbb-3(k) prompted me to think about what sits underneath it: PCR detects an amplification signal at an operator-chosen cycle threshold, not the identity of a virion. Western blot reads a molecular-weight band at a chosen kilodalton value. ELISA reads antibody reactivity at a chosen dilution. These are measurements of properties, not of identity. A trial endpoint built on them is reporting threshold-positive cases — which is a different claim than a reduction in disease.
I wrote it up here in response to your post: https://rkoch.substack.com/p/identifying-the-virus-by-its-weight