Over 900 studies show anti-cancer activity of vitamin D across most cancer types, and randomized controlled trials demonstrate a ~13% reduction in cancer mortality.
Recommended dosage? Most of us have been loading up on vitamin D since before and of course during Covid. I think the typical medical ranges recommended are low. What do you say?
You should get your Vitamin D level checked with a blood test, and not rely on ‘recommendations’. I was taking 10,000 iu for about 3 years, 5,000 is twice a day, along with 250mcg of K2 with each D3 dosage. I had my doctor check my D level in my last blood test….they usually don’t check it for some reason. My Vitamin D level was over 500 (normal is about 100-120). I stopped D3 and K2 for a month, and the level dropped to 350. I now take 4,000 IU once a day with 250mcg of K2. My point is that who knows how someone else’s recommendation will affect you??
Dr John Campbell put video out suggesting we can store 25,000iu a day, so in winter I take 20-25,000iu and pulse 4-12,000iu daily in active summer months. Also plenty of K2, magnesium zinc etc.
I was watching a video, Dr Eric Berg, he showed a medical book that had the dosages of 400,000 !!! His opinion is once big Pharma realized that no one was getting sick, they reduced it all way down to 4,000!! There’s evidence that during major flu outbreaks during turn of the 20th century, Dr’s told people to increase vitamin D dosage to prevent illnesses
Making sure it is D3 not D2 (synthetic) - also helpful is 'lipsomal' which allows supplement to get into our cells - good to take with K2 as well. We take 10,000 iu of D3 daily & spend time out in sun when it's out & the sky is not covered by toxic chemtrails ...
Susan, Liposomal forms of D3 are not needed, unless you eat no fats whatsoever, which would put you into trouble. The old biochemical adage, "like dissolves like" applies here. As I told my patients for decades, take your vitamin D3, whether in an oil based capsule or an acetate form, with a regular meal, or to use the precise clinical term, "with a fatty meal". Save the liposomal expense for hard to absorb substances, like vitamin C, curcumin, and perhaps berberine.
Would you mind sharing a brand of Vit D/k2 that you prefer? So many to choose from and when I research these companies selling this supplement its brings me down rabbit holes. Thank you for your consideration.
I understand your dilemma. The biochemistry can be daunting, especially with commercial concerns often leading the conversation instead of product efficacy.
First, some researchers have suggested D3 can interfere with absorption of K2, so it might be prudent to take them separately, i.e. D3 at breakfast, D2 at lunch.
Several Asian studies have found that 1-3 years of supplementation of K2, in the Mk-4 form, can restore bone loss in post menopausal women.
A product that mimics the study is Mega K2 by Life Extension.
Some argument exists whether The Mk-2 or the Mk-7 form is superior. They are derived from different substrates, and Mk-7 was found to have a longer half-life in vivo, but it also costs more per dose, and in the end has similar biochemical effects. Perhaps for long term use, it might be useful to use a mixed form. For the Mk-7 form, Bronson K2 is cost effective and lab reports shows its stated dosage is accurate.
For Vitamin D3, the field is pretty wide open. For cost effectiveness, Vitacost D3 at 125mcg is a good choice. For unmatched quality in the cGMP space, Thorne's 125mcg capsule is a good choice, just a little more cost.
A few quick thoughts:
For the last 25 years in my practice, I told patients that for pennies a day they could reduce their risk of death from all causes with robust levels of vitamin D. If possible, get some sunshine to obtain it. In winter hit it as a supplement. Get your levels checked, but don't listen to a doc that says your levels are too high at 60,70,80, or 90 ng/dL
Remember that D3 is assisting mineral absorption, and to have a strong mineral lattice on which to hang collagen, it must include Calcium, Magnesium, and Boron. In fact, Magnesium and D3 are synergistic in absorption and activation.
If you drink water from an exceptional mineral spring, you may not need much mineral supplementation. If you drink reverse-osmosis or distilled water, your body will pull minerals from your bones to make the water biochemically active. Consider 1-2mg Boron, 400 Mg Magnesium glycinate, and just eat whole unprocessed foods and the calcium should take care of itself. If your muscles cramp easily, take Epsom salt baths, and put at least 2 pounds of salts in, not a cup or two. Then sleep well as a result.
Also need to take note some people have gene mutations, MTHFR. My Vit D levels were EXTREMELY low. I’m a letter carrier outside in sun all day. Dr was shocked when she saw my results. Ordered 50k once a week. I have since found out I carry a gene mutation, and don’t methylate folate, B vitamins, which kinda has a domino effect, I take methylated vitamins and it’s winter, I take 50k a day.
Yeah, I think the recommended doses that were mentioned in the studies quoted, are also on the lower side. I used to give my kids 2500 IU daily, until I once did a bloodtest on them, and both of them were severely deficient. Maybe its because we are vegans, not sure. Since then we take 5000 daily. No negative side effects, as far as I know.
To see how much vitamin D3 to supplement, on average, per day, to ensure at least 50 ng/mL circulating 25-hydroxyvitamin D all year round, according to body weight and obesity status, please see the recommendations of New Jersey Professor of Medicine Sunil Wimalawansa at: https:// vitamindstopscovid.info/00-evi/#00-how-much. For 70 kg (154 lb) body weight, without obesity, 125 micrograms a day, on average, of vitamin D3 is a good quantity. This is also known as 5000 International Units. This is 5 or more times what governments and many doctors consider necessary - but they are only aiming to attain the 20 ng/mL or so level of circulating 25-hydroxyvitamin D which the kidneys need to play their role in regulating calcium, phosphate and bone metabolism.
This "5000 IU a day" figure sounds high, but it is 1/8000th of a gram. This is a gram every 22 years. Pharma-grade vitamin D3 costs about USD$2.50 a gram ex-factory.
Many types of immune cell can only respond to their changing circumstances properly when they have enough 25-hydroxyvitamin D via diffusion from the bloodstream. 50 ng/mL circulating 25-hydroxyvitamin D, as measured in "vitamin D" blood tests, is sufficient. See .
These cells need 25-hydroxyvitamin D as a raw material input to their 25--hydroxyvitamin D -> calcitriol (1,25-dihydroxyvitamin D) signaling system, which is entirely within the individual cell. This is unrelated to hormonal (endocrine) signaling.
Likewise some cell types use 25-hydroxyvitamin D -> calcitriol paracrine signaling, where by calcitriol produced in one or many cells in a given part of the body, in response to those cells detecting a particular cell-type-specific condition, diffuses into the intercellular fluid, raising the level, locally (I guess a few millimetres or so), significantly above the very low level of calcitriol (0.05 to 0.10 ng/mL) maintained by the kidneys. This localized higher level is detected by other cells - as far as I know, typically of different types - to alter their behaviour.
Both these intracrine and paracrine signaling systems are crucial to the ability of many types of immune cell to change their behaviour in response to their changing circumstances. These are not widely known or understood, there being no peer-reviewed tutorials which explain them. Here is not the place for a tutorial. Please see my (not peer-reviewed) tutorial at: https://vitamindstopscovid.info/00-evi/#02-compounds, or in greater detail, at: https://vitamindstopscovid.info/02-intracrine/.
There's very little vitamin D in food, including that fortified with vitamin D3, or the less effective vitamin D3.
UV-B light can produce sufficient vitamin D3 for full health, but this is only available to most people on Earth in sufficient quantities in the middle of cloud-free summer days, without glass, clothing or sunscreen intervening. Those with dark skin need a lot more UV-B exposure. All UV-B skin exposure damaged DNA and so raises the risk of skin cancer.
Neither vitamin D3 nor 25-hydroxyvitamin D function as hormones. These are not signaling molecules. Calcitriol has one well-known hormonal function: a very low level of circulating calcitriol is maintained by the kidneys as part of the feedback network, also involving osteocytes and the parathyroid gland, which regulates calcium-phosphate-bone metabolism.
The dozens to hundreds of cell types which use 25-hydroxyvitamin D for the above mentioned intracrine and paracrine signaling systems are not significantly affected by the very low level of circulating, hormonal, calcitriol. Nor do they significantly affect this level.
To see why 50 ng/mL (125 nmol/L) is the minimum level of 25-hydroxyvitamin D everyone* should seek to attain, please see this section on Massachusetts General Hospital research from 2014 (Quraishi et al. https://jamanetwork.com/journals/jamasurgery/fullarticle/1782085) which shows, more clearly and directly than any other research, that levels above this provide strong protection against post-operative infections, and the further the level is below this, the greater the risk: https://vitamindstopscovid.info/00-evi/#00-50ngmL.
* The first important exception is infants substantially breast-fed by vitamin D3 and so 25-hydroxyvitamin D replete mothers. The short half-life vitamin D3 and the longer half-life 25-hydroxyvitamin D are both transferred in breast milk. Since 25-hydroxyvitamin D is more easily absorbed into the bloodstream than vitamin D3 (it is more water soluble, due to having two rather than one hydroxyl groups) and since it does not require hydroxylation to raise circulating 25-hydroxyvitamin D, it plays an important role in meeting the 25-hydroxyvitamin D needs of the infant. Measurements of vitamin D3 and 25(OH)D levels in human breast milk vary widely, in part due to the difficulties in measuring such low levels: https://www.frontiersin.org/journals/nutrition/ articles/10.3389/fnut.2023.1229445. One recent study https://www.mdpi.com/2072-6643/13/2/573 found approximately equal amounts of vitamin D3 and 25-hydroxyvitamin D in human breast milk. Since (at least in adults) the liver only coverts about 1/4 of ingested vitamin D3 into circulating 25-hydroxyvitamin D, this means that the bulk of the benefit to the breast-fed child's 25-hydroxyvitamin D comes from the 25-hydroxyvitamin D component of breast milk. This depends on the mother's 25-hydroxyvitamin D level.
The second important exception is people who generate sufficient vitamin D3 in their skin, via UV-B exposure, to attain most or all of the vitamin D3 they need to attain at least 50 ng/mL circulating 25-hydroxyvitamin D all year round. Except in equatorial regions (and even then, there is too little sun in the monsoon season) this can only be achieved with special, dangerous to the eyes and skin, UV-B lamps. While sunlight, including on the skin, is surely important to health via multiple mechanisms, the UV-B required to provide for most or all of our vitamin D3 needs is inherently damaging, since it damages DNA. To rely on this all year, every year, would greatly raise the risk of skin cancer.
I take 5000 IU’s daily with vitamin K and my blood value stays around 65 to 70 NG’s. I do spend my winters in Arizona, which means I don’t have to boost my vitamin D during the winter time if you are in the northern climate.. the key is to have your blood value of vitamin D measured. It can be done at www.grassrootshealth.net via mail order.! Vitamin D is responsible for managing 3000 gene expressions and this is ignored by mainstream medicine because if we boosted our vitamin D blood value for all adults to over 50 ng’s prescription drug sales would drop as well as physicians visits!
An Endocrinologist specializing in the study of Vitamin D says that all North Americans should be supplementing from 9/21 to 3/21 as the angle of the sun is too low to produce as much Vitamin D as in the spring and summer. So take it all year round, no matter how sunny outside. He said in 2015 that Vitamin D deficiency was epidemic. The lockdowns and increased use of internet makes problem worse!
I test myself (blood spot, send to lab) on 3/20 and 9/20 each year. I’m at 51°N. I arrived at these dates as being the maximum period during which I can sunbathe and get Vitamin D at midday (has to be exactly midday either end of this period). I used D minder app but also start to get a faint tan around that time anyway which is useful as a cautious and very steady building of a tan in lock step with the increasing irradiation intensities towards high summer. I’m very brown by mid summer and no burning at all ever (also no seed oils). Doubled blood levels from 30 to 60ng/dL over 2 years. September test shows results of sunbathing. March test shows results of winter supplementation (varied: 4000IU to 8000IU plus K2).
I have also been taking 5000 IU and the corresponding amount of K2 MK7. My measured D was 99, which is high normal according to the normie standards. My doctor suggested I cut the D in half.
If you live in a climate that is sunny, and you spend at least 30 minutes in the sun each day (no sunscreen with skin exposed), you will get enough D3, or require minimal supplementation. During winter months, or in climates with little sun, more supplementation is required. I usually take 5k in summer, as I’m outside every day in the garden, and 10k in winter when there’s less sun and I’m indoors more. Blood tests 2x a yr to test levels. Optimal level is 80 minimum. I run in the 100 range. I take additional supplements, C, K2, zinc, etc, etc, etc. Never got COVID despite zero change in lifestyle and haven’t been sick in over 7 years, which is pretty good for a 72 yr old female!
I run to the sun ever day and I do not use sunscreen. I also take C, Quercetin, Bromelain, and zinc, although I believe I OD'd at 50mg zinc. Be careful with too muck zinc.
The begging question, posed by Nicolas Hulcher... "The only real question left is why public health policy continues to ignore it." Indeed, Nicolas, the best question ever asked.
IT, (VITAMIN D), is deficient in nearly everyone. I understand that EVERY PERSON tested, who died from Covid 19, was found to be deficient in Vitamin D.
Now, Nicolas Hulcher has revealed that cancer is more likely in a Vitamin D deficient setting.
I also understand that Vitamin D, quercetin and zinc are needed together to make all components effective at preventing disease. Zinc is found in mushrooms. Quercetin is found in onions. Vitamin D is found in animal sources like fish and eggs. K2 is found in fermented foods.
The medical system is an abject failure in nutrition. Thanks for educating the doctors in the world, Nicolas, you are a great man in our view. Merry Christmas to you and your family, and your colleagues.
"The only real question left is why public health policy continues to ignore it." Indeed, Nicolas, the best question ever asked."
It is a great question, but not difficult to answer.... D3 has been a top of Big Pharma's hit list for decades. They can't have people running around in better health. It's bad for business. A PhD out in California explained not too long ago to Dr. Pierre Kory,... "what they're doing to Ivermectin, they have been doing to D3 for decades."
This is why I eat at least 4 eggs daily. 126 eggs every month. 1512 eggs a year. Eggs are loaded with Vitamin D. Egg whites protect the fetus, the egg yolk from bacteria, what do you think it does to your digestive system and subsequently your organs that obtain the nutrients you consume via osmosis? Your organs retain the barrier properties of egg whites protecting them from harmful bacterium. It also helps SIGNIFICANTLY to purge your microbiome of harmful bacterium, parasites, and worms with Praziquantel, Ivermectin, Menbendazol/Fenbendazol and with 3-5 day water fasting.
Pro tip: Fasting doesn't start until there is nothing left in your digestive system meaning 24-36 hours AFTER the very last thing you ate and I enjoy a 5 day fast with naturally flavored sparkling water. It tastes great if you buy the right brand, makes you feel significantly less hungry, and you can drink as much sparkling water as you want. Take it from me who’s lost 130 pounds fasting, dieting, and consuming the aforementioned products to cleanse my system in just 8 months. I’m healthier than I’ve been in years and I feel better too eating 4 eggs daily.
Eggs are the only food you can eat a ton of and still lose weight, they're filling, versatile in the kitchen, and naturally loaded with best nurtrients to make you healthier than ever before. Eggs are incredible. Eat more eggs, your body will thank you.
I take it daily, but my levels always remain low or at the lower end of normal. What dosage do you recommend, and are there any particular brands you suggest? Thank you!
Question: How much are you taking daily, and when do you take it?
Many brands are fine. I switch back and forth with Life Extension and Thorne products, but there are many others that show proper dose and good manufacturing practices, and ratings of some are found on ConsumerLab, which does independent testing.
Blood level is ultimately more important than dose, given how much people can vary. Sunshine/UVB-produced vitamin D auto-regulates (can't overdose, that is) and achieves documented levels up to 120 ng/mL. All documented toxicity appears to be in excess of 200 ng/mL, so following nature's lead, one would likely benefit most from a level somewhere around 100 ng/mL +/-. In addition to K2, magnesium, zinc, iodine, boron all important cofactors for optimal safety and efficacy. Many "can't tolerate Vitamin D" cases are not overdose of vitamin D but rather deficits in adequate cofactor availability. Ironically, the then "Institute of Medicine" advisory group "VITAL Study" of 2000 IU of D3 + 1000 mg Fish oil daily vs. placebo found an even greater 17-25% decrease in deaths from cancer in less than 6 years, but concluded the vitamin D had "no significant effect" because they set the bar at more than 20% reduction in CASES in less than 6 years and "only" had 10% fewer cases in the study group:https://www.vitalstudy.org/findings.html
Note, this is the organization which set the RDA at 1000-2000 IU per day, the "safe upper limit" at 4000 IU per day and changed the decades-long range of normal blood serum 25(OH)D3 level from 30-100ng/mL down to 20-50ng/mL. The argument for the latter was something along the lines that the longstanding range would mean about 2/3 of the world's population was chronically deficient, and that just couldn't be true by their take, so they basically defined the contemporary North American adult as determining the normal range. Uh huh...all those office- cubicle-working, clothes-wearing, concrete-canyon-dwelling, sun-screened people are the equivalent of the Paleo Human at their best...yeah....
The sickest “un-American” people are in power in USA. Keeping power and the money flowing is the only thing they value, so they are morally unfit to be in power. They must be removed to protect Rights and good people everywhere.
Most people are short of K2 (Mk-7) as well. It protects you from hypercalcemia, which is the main threat with taking excessive amounts of D3. But Mk-7 has many benefits for the entire body in its own right. It is basically the forgotten nutrient, critical for good health.... https://ohbaby.substack.com/p/incredible-benefits-of-k2-the-forgotten
My understanding is that K2 needed to get calcium out of blood vessels and into bone. I assume calcium in blood vessels cause deposits. NB engineer not medic.
Jesus was a Jew. He was killed under the Romans' judicial system. The cross is a Roman method of execution.
His disciples, his first followers, who were primarily responsible for carrying his life's story and teachings to others then and eventually us today were Jewish.
The Cheif Priests and Sadducees (elites we might say) were as unforgivingly observant of God's law as they were feindishly and relentlessly outspoken against Jesus.
They kept the Law, but discarded the Spirit of the Law. They used a tool that was created by God (YAHWEH, the God of Abraham, Isaac, Jacob, and Jesus) for the good of man and twisted it to gain status and defend their power.
The hate of that Jew (Jesus of Nazareth born in Bethlehem) and jealousy of the followers he was amassing led them to speak out publicly and denounce him until the point of his death.
I pray, and I encourage us all to pray (as I believe Charlie Kirk did), we do not permit the hate and jealousy in and amongst us lead any of us to that point again to today (any more than it already has). I pray (especially if we claim to be doing so in the name of God) we keep the Spirit of the Law and use it as He intended, for the betterment of mankind, to lead us closer to God, and not to disparage to the point of death some scapegoat of our choosing as a substitute for responsibly attending to our own shortcomings.
Recommended dosage? Most of us have been loading up on vitamin D since before and of course during Covid. I think the typical medical ranges recommended are low. What do you say?
You should get your Vitamin D level checked with a blood test, and not rely on ‘recommendations’. I was taking 10,000 iu for about 3 years, 5,000 is twice a day, along with 250mcg of K2 with each D3 dosage. I had my doctor check my D level in my last blood test….they usually don’t check it for some reason. My Vitamin D level was over 500 (normal is about 100-120). I stopped D3 and K2 for a month, and the level dropped to 350. I now take 4,000 IU once a day with 250mcg of K2. My point is that who knows how someone else’s recommendation will affect you??
Dr John Campbell put video out suggesting we can store 25,000iu a day, so in winter I take 20-25,000iu and pulse 4-12,000iu daily in active summer months. Also plenty of K2, magnesium zinc etc.
Always D3 plus K2
I am so happy reading this thread. For a while, I didn't think anyone was getting the message on D3, along with K2. It could have saved millions of lives during the pandemic.... https://ohbaby.substack.com/p/the-incredible-evil-in-suppressing
I was watching a video, Dr Eric Berg, he showed a medical book that had the dosages of 400,000 !!! His opinion is once big Pharma realized that no one was getting sick, they reduced it all way down to 4,000!! There’s evidence that during major flu outbreaks during turn of the 20th century, Dr’s told people to increase vitamin D dosage to prevent illnesses
I love Dr Berg. I watched the same video. I take about 10,000 IU daily and check my levels every 6 months. It's usually between 70 and 80
Making sure it is D3 not D2 (synthetic) - also helpful is 'lipsomal' which allows supplement to get into our cells - good to take with K2 as well. We take 10,000 iu of D3 daily & spend time out in sun when it's out & the sky is not covered by toxic chemtrails ...
Susan, Liposomal forms of D3 are not needed, unless you eat no fats whatsoever, which would put you into trouble. The old biochemical adage, "like dissolves like" applies here. As I told my patients for decades, take your vitamin D3, whether in an oil based capsule or an acetate form, with a regular meal, or to use the precise clinical term, "with a fatty meal". Save the liposomal expense for hard to absorb substances, like vitamin C, curcumin, and perhaps berberine.
Thank you much Maha
for this info ...
Would you mind sharing a brand of Vit D/k2 that you prefer? So many to choose from and when I research these companies selling this supplement its brings me down rabbit holes. Thank you for your consideration.
I understand your dilemma. The biochemistry can be daunting, especially with commercial concerns often leading the conversation instead of product efficacy.
First, some researchers have suggested D3 can interfere with absorption of K2, so it might be prudent to take them separately, i.e. D3 at breakfast, D2 at lunch.
Several Asian studies have found that 1-3 years of supplementation of K2, in the Mk-4 form, can restore bone loss in post menopausal women.
A product that mimics the study is Mega K2 by Life Extension.
Some argument exists whether The Mk-2 or the Mk-7 form is superior. They are derived from different substrates, and Mk-7 was found to have a longer half-life in vivo, but it also costs more per dose, and in the end has similar biochemical effects. Perhaps for long term use, it might be useful to use a mixed form. For the Mk-7 form, Bronson K2 is cost effective and lab reports shows its stated dosage is accurate.
For Vitamin D3, the field is pretty wide open. For cost effectiveness, Vitacost D3 at 125mcg is a good choice. For unmatched quality in the cGMP space, Thorne's 125mcg capsule is a good choice, just a little more cost.
A few quick thoughts:
For the last 25 years in my practice, I told patients that for pennies a day they could reduce their risk of death from all causes with robust levels of vitamin D. If possible, get some sunshine to obtain it. In winter hit it as a supplement. Get your levels checked, but don't listen to a doc that says your levels are too high at 60,70,80, or 90 ng/dL
Remember that D3 is assisting mineral absorption, and to have a strong mineral lattice on which to hang collagen, it must include Calcium, Magnesium, and Boron. In fact, Magnesium and D3 are synergistic in absorption and activation.
If you drink water from an exceptional mineral spring, you may not need much mineral supplementation. If you drink reverse-osmosis or distilled water, your body will pull minerals from your bones to make the water biochemically active. Consider 1-2mg Boron, 400 Mg Magnesium glycinate, and just eat whole unprocessed foods and the calcium should take care of itself. If your muscles cramp easily, take Epsom salt baths, and put at least 2 pounds of salts in, not a cup or two. Then sleep well as a result.
Good luck.
"MK-4 is unique among the menaquinones in that it is not synthesized by bacteria. Instead, MK-4 is alkylated from menadione (vitamin K3), a synthetic form of vitamin K that is present in animal feeds, or is the product of tissue-specific conversion directly from dietary phylloquinone [K1], with menadione as the postulated intermediate." https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/role-of-menaquinones-vitamin-k2-in-human-health/5B9F317B526629D8BA77B6435F1E5509
Stick with Mk-7, better absorption, longer half life, better extra-hepatic activity, blah-blah-blah... https://ohbaby.substack.com/p/incredible-benefits-of-k2-the-forgotten
Thank you so much for your thorough explanation. I really appreciate it.
Tips and examples on how to purchase quality D3... https://ohbaby.substack.com/p/what-you-thought-you-knew-of-d3-hardly/comment/64381480
With K2, stick with Mk-7, not Mk-4. It's just better.... https://ohbaby.substack.com/p/incredible-benefits-of-k2-the-forgotten
Also need to take note some people have gene mutations, MTHFR. My Vit D levels were EXTREMELY low. I’m a letter carrier outside in sun all day. Dr was shocked when she saw my results. Ordered 50k once a week. I have since found out I carry a gene mutation, and don’t methylate folate, B vitamins, which kinda has a domino effect, I take methylated vitamins and it’s winter, I take 50k a day.
I’ve been taking 5000IU of D 3 per day for 15 years, recommended by my rheumatologist for bone pain. It also helps depression.
You have a good Rheumatologist, Nancy. And as you know, D3 also reduces the risk of death from quite a few other issues.
It was well reported that during the COVID scam, Fauci was taking 10,000iu a day. Of course, he never spoke about it.
Currently taking 10,000 in per day as well.
Yeah, I think the recommended doses that were mentioned in the studies quoted, are also on the lower side. I used to give my kids 2500 IU daily, until I once did a bloodtest on them, and both of them were severely deficient. Maybe its because we are vegans, not sure. Since then we take 5000 daily. No negative side effects, as far as I know.
To see how much vitamin D3 to supplement, on average, per day, to ensure at least 50 ng/mL circulating 25-hydroxyvitamin D all year round, according to body weight and obesity status, please see the recommendations of New Jersey Professor of Medicine Sunil Wimalawansa at: https:// vitamindstopscovid.info/00-evi/#00-how-much. For 70 kg (154 lb) body weight, without obesity, 125 micrograms a day, on average, of vitamin D3 is a good quantity. This is also known as 5000 International Units. This is 5 or more times what governments and many doctors consider necessary - but they are only aiming to attain the 20 ng/mL or so level of circulating 25-hydroxyvitamin D which the kidneys need to play their role in regulating calcium, phosphate and bone metabolism.
This "5000 IU a day" figure sounds high, but it is 1/8000th of a gram. This is a gram every 22 years. Pharma-grade vitamin D3 costs about USD$2.50 a gram ex-factory.
Many types of immune cell can only respond to their changing circumstances properly when they have enough 25-hydroxyvitamin D via diffusion from the bloodstream. 50 ng/mL circulating 25-hydroxyvitamin D, as measured in "vitamin D" blood tests, is sufficient. See .
These cells need 25-hydroxyvitamin D as a raw material input to their 25--hydroxyvitamin D -> calcitriol (1,25-dihydroxyvitamin D) signaling system, which is entirely within the individual cell. This is unrelated to hormonal (endocrine) signaling.
Likewise some cell types use 25-hydroxyvitamin D -> calcitriol paracrine signaling, where by calcitriol produced in one or many cells in a given part of the body, in response to those cells detecting a particular cell-type-specific condition, diffuses into the intercellular fluid, raising the level, locally (I guess a few millimetres or so), significantly above the very low level of calcitriol (0.05 to 0.10 ng/mL) maintained by the kidneys. This localized higher level is detected by other cells - as far as I know, typically of different types - to alter their behaviour.
Both these intracrine and paracrine signaling systems are crucial to the ability of many types of immune cell to change their behaviour in response to their changing circumstances. These are not widely known or understood, there being no peer-reviewed tutorials which explain them. Here is not the place for a tutorial. Please see my (not peer-reviewed) tutorial at: https://vitamindstopscovid.info/00-evi/#02-compounds, or in greater detail, at: https://vitamindstopscovid.info/02-intracrine/.
There's very little vitamin D in food, including that fortified with vitamin D3, or the less effective vitamin D3.
UV-B light can produce sufficient vitamin D3 for full health, but this is only available to most people on Earth in sufficient quantities in the middle of cloud-free summer days, without glass, clothing or sunscreen intervening. Those with dark skin need a lot more UV-B exposure. All UV-B skin exposure damaged DNA and so raises the risk of skin cancer.
Neither vitamin D3 nor 25-hydroxyvitamin D function as hormones. These are not signaling molecules. Calcitriol has one well-known hormonal function: a very low level of circulating calcitriol is maintained by the kidneys as part of the feedback network, also involving osteocytes and the parathyroid gland, which regulates calcium-phosphate-bone metabolism.
The dozens to hundreds of cell types which use 25-hydroxyvitamin D for the above mentioned intracrine and paracrine signaling systems are not significantly affected by the very low level of circulating, hormonal, calcitriol. Nor do they significantly affect this level.
To see why 50 ng/mL (125 nmol/L) is the minimum level of 25-hydroxyvitamin D everyone* should seek to attain, please see this section on Massachusetts General Hospital research from 2014 (Quraishi et al. https://jamanetwork.com/journals/jamasurgery/fullarticle/1782085) which shows, more clearly and directly than any other research, that levels above this provide strong protection against post-operative infections, and the further the level is below this, the greater the risk: https://vitamindstopscovid.info/00-evi/#00-50ngmL.
* The first important exception is infants substantially breast-fed by vitamin D3 and so 25-hydroxyvitamin D replete mothers. The short half-life vitamin D3 and the longer half-life 25-hydroxyvitamin D are both transferred in breast milk. Since 25-hydroxyvitamin D is more easily absorbed into the bloodstream than vitamin D3 (it is more water soluble, due to having two rather than one hydroxyl groups) and since it does not require hydroxylation to raise circulating 25-hydroxyvitamin D, it plays an important role in meeting the 25-hydroxyvitamin D needs of the infant. Measurements of vitamin D3 and 25(OH)D levels in human breast milk vary widely, in part due to the difficulties in measuring such low levels: https://www.frontiersin.org/journals/nutrition/ articles/10.3389/fnut.2023.1229445. One recent study https://www.mdpi.com/2072-6643/13/2/573 found approximately equal amounts of vitamin D3 and 25-hydroxyvitamin D in human breast milk. Since (at least in adults) the liver only coverts about 1/4 of ingested vitamin D3 into circulating 25-hydroxyvitamin D, this means that the bulk of the benefit to the breast-fed child's 25-hydroxyvitamin D comes from the 25-hydroxyvitamin D component of breast milk. This depends on the mother's 25-hydroxyvitamin D level.
The second important exception is people who generate sufficient vitamin D3 in their skin, via UV-B exposure, to attain most or all of the vitamin D3 they need to attain at least 50 ng/mL circulating 25-hydroxyvitamin D all year round. Except in equatorial regions (and even then, there is too little sun in the monsoon season) this can only be achieved with special, dangerous to the eyes and skin, UV-B lamps. While sunlight, including on the skin, is surely important to health via multiple mechanisms, the UV-B required to provide for most or all of our vitamin D3 needs is inherently damaging, since it damages DNA. To rely on this all year, every year, would greatly raise the risk of skin cancer.
I take 5000 IU’s daily with vitamin K and my blood value stays around 65 to 70 NG’s. I do spend my winters in Arizona, which means I don’t have to boost my vitamin D during the winter time if you are in the northern climate.. the key is to have your blood value of vitamin D measured. It can be done at www.grassrootshealth.net via mail order.! Vitamin D is responsible for managing 3000 gene expressions and this is ignored by mainstream medicine because if we boosted our vitamin D blood value for all adults to over 50 ng’s prescription drug sales would drop as well as physicians visits!
An Endocrinologist specializing in the study of Vitamin D says that all North Americans should be supplementing from 9/21 to 3/21 as the angle of the sun is too low to produce as much Vitamin D as in the spring and summer. So take it all year round, no matter how sunny outside. He said in 2015 that Vitamin D deficiency was epidemic. The lockdowns and increased use of internet makes problem worse!
Problem is that life style issues has driven down D values to subnormal values that have been falsely stated as being normal.
Correct!
I test myself (blood spot, send to lab) on 3/20 and 9/20 each year. I’m at 51°N. I arrived at these dates as being the maximum period during which I can sunbathe and get Vitamin D at midday (has to be exactly midday either end of this period). I used D minder app but also start to get a faint tan around that time anyway which is useful as a cautious and very steady building of a tan in lock step with the increasing irradiation intensities towards high summer. I’m very brown by mid summer and no burning at all ever (also no seed oils). Doubled blood levels from 30 to 60ng/dL over 2 years. September test shows results of sunbathing. March test shows results of winter supplementation (varied: 4000IU to 8000IU plus K2).
I have also been taking 5000 IU and the corresponding amount of K2 MK7. My measured D was 99, which is high normal according to the normie standards. My doctor suggested I cut the D in half.
I am taking 8,500 iu/day and my blood value is 80ng/ml.
If you live in a climate that is sunny, and you spend at least 30 minutes in the sun each day (no sunscreen with skin exposed), you will get enough D3, or require minimal supplementation. During winter months, or in climates with little sun, more supplementation is required. I usually take 5k in summer, as I’m outside every day in the garden, and 10k in winter when there’s less sun and I’m indoors more. Blood tests 2x a yr to test levels. Optimal level is 80 minimum. I run in the 100 range. I take additional supplements, C, K2, zinc, etc, etc, etc. Never got COVID despite zero change in lifestyle and haven’t been sick in over 7 years, which is pretty good for a 72 yr old female!
I run to the sun ever day and I do not use sunscreen. I also take C, Quercetin, Bromelain, and zinc, although I believe I OD'd at 50mg zinc. Be careful with too muck zinc.
Sun gives us vit D… the skincare businesses sold us “sun is bad”…..
The begging question, posed by Nicolas Hulcher... "The only real question left is why public health policy continues to ignore it." Indeed, Nicolas, the best question ever asked.
IT, (VITAMIN D), is deficient in nearly everyone. I understand that EVERY PERSON tested, who died from Covid 19, was found to be deficient in Vitamin D.
Now, Nicolas Hulcher has revealed that cancer is more likely in a Vitamin D deficient setting.
I also understand that Vitamin D, quercetin and zinc are needed together to make all components effective at preventing disease. Zinc is found in mushrooms. Quercetin is found in onions. Vitamin D is found in animal sources like fish and eggs. K2 is found in fermented foods.
The medical system is an abject failure in nutrition. Thanks for educating the doctors in the world, Nicolas, you are a great man in our view. Merry Christmas to you and your family, and your colleagues.
"The only real question left is why public health policy continues to ignore it." Indeed, Nicolas, the best question ever asked."
It is a great question, but not difficult to answer.... D3 has been a top of Big Pharma's hit list for decades. They can't have people running around in better health. It's bad for business. A PhD out in California explained not too long ago to Dr. Pierre Kory,... "what they're doing to Ivermectin, they have been doing to D3 for decades."
https://ohbaby.substack.com/p/the-incredible-evil-in-suppressing
This is why I eat at least 4 eggs daily. 126 eggs every month. 1512 eggs a year. Eggs are loaded with Vitamin D. Egg whites protect the fetus, the egg yolk from bacteria, what do you think it does to your digestive system and subsequently your organs that obtain the nutrients you consume via osmosis? Your organs retain the barrier properties of egg whites protecting them from harmful bacterium. It also helps SIGNIFICANTLY to purge your microbiome of harmful bacterium, parasites, and worms with Praziquantel, Ivermectin, Menbendazol/Fenbendazol and with 3-5 day water fasting.
Pro tip: Fasting doesn't start until there is nothing left in your digestive system meaning 24-36 hours AFTER the very last thing you ate and I enjoy a 5 day fast with naturally flavored sparkling water. It tastes great if you buy the right brand, makes you feel significantly less hungry, and you can drink as much sparkling water as you want. Take it from me who’s lost 130 pounds fasting, dieting, and consuming the aforementioned products to cleanse my system in just 8 months. I’m healthier than I’ve been in years and I feel better too eating 4 eggs daily.
Eggs are the only food you can eat a ton of and still lose weight, they're filling, versatile in the kitchen, and naturally loaded with best nurtrients to make you healthier than ever before. Eggs are incredible. Eat more eggs, your body will thank you.
I take it daily, but my levels always remain low or at the lower end of normal. What dosage do you recommend, and are there any particular brands you suggest? Thank you!
I take 5000 IU per day.
I take 5,000iu's a day.
My levels are always perfect, but, for chemo prevention, the amounts of 50,000iu seem a bit excessive.
Just curious as to your thoughts on this ?
Question: How much are you taking daily, and when do you take it?
Many brands are fine. I switch back and forth with Life Extension and Thorne products, but there are many others that show proper dose and good manufacturing practices, and ratings of some are found on ConsumerLab, which does independent testing.
Fu.k Usreal
Which is just one more reason they are blanketing the sun. We NEED it!
Blood level is ultimately more important than dose, given how much people can vary. Sunshine/UVB-produced vitamin D auto-regulates (can't overdose, that is) and achieves documented levels up to 120 ng/mL. All documented toxicity appears to be in excess of 200 ng/mL, so following nature's lead, one would likely benefit most from a level somewhere around 100 ng/mL +/-. In addition to K2, magnesium, zinc, iodine, boron all important cofactors for optimal safety and efficacy. Many "can't tolerate Vitamin D" cases are not overdose of vitamin D but rather deficits in adequate cofactor availability. Ironically, the then "Institute of Medicine" advisory group "VITAL Study" of 2000 IU of D3 + 1000 mg Fish oil daily vs. placebo found an even greater 17-25% decrease in deaths from cancer in less than 6 years, but concluded the vitamin D had "no significant effect" because they set the bar at more than 20% reduction in CASES in less than 6 years and "only" had 10% fewer cases in the study group:https://www.vitalstudy.org/findings.html
Note, this is the organization which set the RDA at 1000-2000 IU per day, the "safe upper limit" at 4000 IU per day and changed the decades-long range of normal blood serum 25(OH)D3 level from 30-100ng/mL down to 20-50ng/mL. The argument for the latter was something along the lines that the longstanding range would mean about 2/3 of the world's population was chronically deficient, and that just couldn't be true by their take, so they basically defined the contemporary North American adult as determining the normal range. Uh huh...all those office- cubicle-working, clothes-wearing, concrete-canyon-dwelling, sun-screened people are the equivalent of the Paleo Human at their best...yeah....
The sickest “un-American” people are in power in USA. Keeping power and the money flowing is the only thing they value, so they are morally unfit to be in power. They must be removed to protect Rights and good people everywhere.
WAKE UP PEOPLE
USS Liberty
Blocking you.
What happens if you only take vitamin D3 supplements without any vitamin K2? Is it better than nothing to take just vitamin D3?
Most people are short of K2 (Mk-7) as well. It protects you from hypercalcemia, which is the main threat with taking excessive amounts of D3. But Mk-7 has many benefits for the entire body in its own right. It is basically the forgotten nutrient, critical for good health.... https://ohbaby.substack.com/p/incredible-benefits-of-k2-the-forgotten
My understanding is that K2 needed to get calcium out of blood vessels and into bone. I assume calcium in blood vessels cause deposits. NB engineer not medic.
Okay, but both also good to prevent breast cancer. I take Super K from Life Extension that I buy at Pure Formulas. I buy Vitamin D3 at Costco.
Jews killed Jesus
Take some Vitamin D for your depression and Magnesium for your crankiness. Seek help!
Hey, I was going to mention how Mg and D3 are interdependent for activation and absorption. Even for trolls like Paul, I guess.
Jesus was a Jew. He was killed under the Romans' judicial system. The cross is a Roman method of execution.
His disciples, his first followers, who were primarily responsible for carrying his life's story and teachings to others then and eventually us today were Jewish.
The Cheif Priests and Sadducees (elites we might say) were as unforgivingly observant of God's law as they were feindishly and relentlessly outspoken against Jesus.
They kept the Law, but discarded the Spirit of the Law. They used a tool that was created by God (YAHWEH, the God of Abraham, Isaac, Jacob, and Jesus) for the good of man and twisted it to gain status and defend their power.
The hate of that Jew (Jesus of Nazareth born in Bethlehem) and jealousy of the followers he was amassing led them to speak out publicly and denounce him until the point of his death.
I pray, and I encourage us all to pray (as I believe Charlie Kirk did), we do not permit the hate and jealousy in and amongst us lead any of us to that point again to today (any more than it already has). I pray (especially if we claim to be doing so in the name of God) we keep the Spirit of the Law and use it as He intended, for the betterment of mankind, to lead us closer to God, and not to disparage to the point of death some scapegoat of our choosing as a substitute for responsibly attending to our own shortcomings.
Since the Trudeau and cv19 era, Canada wants to halt and block all natural health products — trenchant people dead and ill, not alive and healthy.