Tonight on Stinchfield Tonight, I broke down one of the most alarming scientific frontiers in modern biotechnology: the push, now openly funded by Big Tech, to gene-edit human embryos and manufacture genetically engineered children.
Based on previously published evidence, this will end in catastrophe. This entire effort is founded on a fatal scientific illusion—the idea that we can safely re-write the human genome at the earliest stages of life without profound consequences.
Zuccaro et al (2020): The Study That Should Have Ended All Talk of GMO Babies
Zuccaro et al (2020) attempted to “fix” a single mutation in a human embryo using CRISPR-Cas9. Specifically, they targeted a paternal frameshift mutation in the EYS gene—a mutation associated with inherited retinal degeneration—intending to cut the defective sequence and allow the embryo’s own repair machinery to restore a normal, wild-type allele.
Here is what happened:
Entire chromosomes were lost
Whole chromosomal arms vanished
Cells within the same embryo became genetically different (mosaic)
Some cells had intact DNA, others were catastrophically damaged
The embryo fractured into incompatible genetic lineages
Instead of fixing a mutation, CRISPR created massive genomic instability. Even the authors warned that human germline editing is unsafe and nowhere near ready for human use.
The Preventive / Sam Altman Program
The start-up Sam Altman is financing (Preventive) claims it will use embryo gene editing to “end genetic disease.” In reality, they are opening the door to:
Deadly pregnancy outcomes
Babies born with severe developmental malformations
Generational genetic instability
Permanent alterations to the human germline
A dystopian future of genetically modified humans
As I warned on Stinchfield Tonight, the first iterations of these edited embryos—if ever brought to term—would almost certainly die or develop catastrophic deformities. To evade oversight, Preventive plans to offshore embryo editing to the UAE or other permissive jurisdictions.
Human embryo gene editing is catastrophically unsafe and utterly unfit for real-world use.
Epidemiologist and Foundation Administrator, McCullough Foundation
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